I envision a set of 12 mouths, all made from the exact same nodes, in a switch layer, and one "Smiley/Frowny" Smart Dial, to control the happiness/sadness factor. I've successfully made such a dial, but it only affected the mouth I adjusted to make it, not all of them, like I was hoping.
It should work. My recent rigs at work have a mouth switch containing standard 'neutral' phoneme drawings which can gradually change expressions by turning an 'Emotion' SBD. (i.e., dial to right for 'happier', left for 'sadder/madder'.) The individual mouth drawings don't need to have the same point count or order for this effect. Each mouth drawing layer or group can have its own animation associated to the SBD. You just need to create a 'corners up' and 'corners down' animation for each side of the SBD, which only takes a couple of seconds to create using the magnet tool.
You only need to use the same points for each layer if you intend to interpolate between the mouth shapes
layers themselves. Personally, I don't bother with that--this kind of blending tends to look kinda 'mushy' during lip sync animations. Trying to preserve the points also becomes troublesome and limiting for every new mouth shape I decide to add. And, as already mentioned, it's not necessary to do this for an 'Emotion' SBD.
I also find I can draw better mouth shapes using the appropriate number of points for each pose. By freeing myself from the point order restriction, I can also use multiple layers (mouth, teeth, tongue, mask, etc.,) inside a mouth shape
group inside the mouth switch for more pose possibilities.
To transition between mouth shapes (layers or groups), I prefer to push the points for a frame or two using the Magnet tool or by simply transforming (squash, stretch, slant) the mouth switch layer itself between phoneme keyframes. (The latter is faster and less messy.) This 'in-between' tweak takes only takes a few seconds to add, and the keys are reusable as needed. When it's done well, I think, this approach looks more natural than shape interpolation.
BTW, I normally add 'Emotion' animations to the SBD only for the standard phonemes. For 'special' mouths shapes (i.e., grimace, yell, big smile, etc.,) I prefer to make variations as needed and add them to the bottom of the Switch layer. The 'special' mouths tend to be exaggerated emotions so I let them be standalone drawings rather than combo drawings for the SBD.
Hope this helps.