1) It would be great if the select and transform tool can be be toggled with just the press of one key and than reverts back to, lets say the select key automatically.. its hard to change these two tools even with the shortcut all the time..specially when doing lot of editing
2) Navigating the timeline is hard. Sometimes when we zoom in the time line jumps to frame 0 instead of zooming in on the playhead.
3) It would be great if the shortcut keys were the same as other popular softwares we use. Specially the video and effects ones..
4) I could not find a short cut for ZOOM and PAN which is like two of the most used tool in computer drawing. One great feature we saw was hittin esc key twice zoomed it right in to the object selected.. this is fantastic..
5) The onion skin option is great but we keep hittin on the onion skin bar while trying to navigate the timeline. its frustrating specially if the timeline is zoomed out and we have to zoom in to disable the onion skin on that frame. But the way we can onion skin anyframe so easily is awsome. Maybe a button to shy the onion skin or reset all.
6) speaking of reset. We were unable to find a way to automatically delete all the keyframes we placed for a each layer.
7) We might be wrong here but is there an animatin preview we can do. when we do a preview we only see one single frame. It would be great if we can do a very low resolution movie preview to check the motion. even if it does render it to the disk. Just having to render at a low resolution and going and playing is too many clicks

9) Instead of showing the layers as a thin line it would be great if you can have a slighty wider line. easier to handle. (we dont work on large dual monitors

10) It will also be great if we can color code the elements in the Bin so that navigation is easier.
Anyways these are just our few thoughts on moho..w we have used it only for a few weeks so we might be completely wrong on this..if anyone has a solution for those stuff please let us know.. this is the best 2d character animation prog we have used. Fantastic...