Moho is actually quite intuitive but it is very different from composting programs like Ae. For example, while both Moho and Ae use layers, Moho supports grouping layers like Photoshop but Ae does not. Ae does support precomps but in practice, that's a very different thing from groups...a precomp is more like importing a Reference project in Moho. There are different strengths and weaknesses with each program, and I suggest not expect Moho to work exactly like Ae. (That's a mistake I made back when I started learning Moho.)
Once you understand Moho's UI and workflow, the program works remarkably well with programs like AE. (Most of the Moho animations I create at my workplace are comped in Ae.)
Regarding scale compensation for strokes, there are a couple of ways to deal with this:
In the
layer settings, enabling Scale Compensation will scale the lines as the layer or the parent layer scales up and down. This option is on by default. If you're not seeing this effect, be sure to click Apply before closing the window. (It
should accept it even when you don't click Apply and close the window, but try this to be sure.)
When the option is disabled, the line weight remain constant as you scale the layers.
Note that enabling the option in a group settings does not affect the child layers. If you want to affect multiple layers, you need to change the settings to each layer. The easy way to do this is the select the layers you want to affect, and make sure Copy All General Settings To Other Selected Layers is enabled before clicking Apply.
The one issue with the above is that if your production has standard style guides for line weights, scaling the art may violate the style guides. In this case, you might consider using Custom Styles instead. This way, you can set or animate the line weight specifically to follow the style guide exactly.
To do this, set up a style that affects only the strokes weights and apply this to shapes using this stroke. Moho allows you to combine multiple styles and it's possible to set this feature so the line weights can be controlled globally though the Style window without affecting fills, line colors, etc.
Sometimes I'll use a custom style to compensate for extreme scaling caused by Scale Compensation. For example, if I scale a character down too much, the lines may become too faint. But if I had setup a custom style for my line weights, I can easily 'grow' all the lines at once. (In other words, compensate for the compensation.)
Hope this helps.