Here is a link to a layer script I created a long time ago for DK. It might be of some use for those of you using Anime Studio for frame by frame image sequence animation.
image-layer-sequencer-layer-script
Basically all it does is replace the source image of a single image layer in Anime Studio based on the frame number. So if you have a folder with a numbered image sequence, you would only need the first image as an image layer, embed this layer script, and then when you play or render the animation each frame will show the next image in the sequence. You only need 1 image layer so there isn't a huge memory overhead loading a pile of images.
Currently It doesn't have any options, just playback from frame 1 of the sequence. You can change a single variable in the script file to change the playback frame rate (updates the image every X frame instead of every 1 frame).
I want to add some new features to make it work better based on for example, layer visibility or switch layers. So maybe you could have a series of short sequences in a switch layer, each one linked to a different image sequence, that only playback when activated (one image layer in the switch with the embedded script). I could add in the ability to loop a sequence or offset the start and stop.
The tricky part is this is a layer script so I would need to use the metadata storage for layer settings and values. Probably would need a new tool to go along with it to change values. I don't actually do any fbf animation with Anime Studio but this script was so simple and fun I should take a stab at making it more useful. There seems to be a lot of people who need this functionality.